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The Impact of Chlamydia Treatment During Pregnancy on Birth Defects in New York State.


ABSTRACT:

Background

Chlamydia trachomatis (CT) diagnoses are highest among females of reproductive age. Yet, little is known about adverse infant outcomes associated with treatment for CT infections during pregnancy, including birth defects.

Methods

Using de-identified matched data from the New York State (NYS) Sexually Transmitted Infection Surveillance Registry and live births reported to the NYS Birth Defects Registry from 2010 to 2020, we conducted a retrospective cohort study among pregnancies with one first-trimester CT diagnosis to assess the impact of adequate CT treatment on the risk of selected birth defects.

Results

Pregnancies with evidence of adequate CT treatment during the first trimester were more likely (adjusted risk ratio [ARR]: 3.0, 95% confidence interval

SUBMITTER: Boos EM 

PROVIDER: S-EPMC12816446 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature