Forced vital capacity as a survival predictor in systemic sclerosis-associated pulmonary hypertension.

ABSTRACT:

Background

Pulmonary hypertension associated with systemic sclerosis (SSc-PH) carries a significant risk of mortality. Although interstitial lung disease (ILD) often coexists with SSc-PH, its impact on prognosis varies considerably depending on disease extension. The prognostic implications of different degrees of functional impairment secondary to ILD in patients with SSc-PH remain poorly understood.

Objectives

This study aimed to stratify patients with SSc-PH according to their functional parameters and to identify potential prognostic factors in different patterns of ILD extension.

Design

A retrospective study was conducted on consecutive patients with SSc-PH diagnosed according to the European Society of Cardiology/European Respiratory Society guidelines for PH si

SUBMITTER: Iannone C 

PROVIDER: S-EPMC12816533 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature