Dietary patterns, physical activity, and risk of urinary tract diseases: a two sample Mendelian randomization analysis.

ABSTRACT:

Background

Previous studies have found associations between dietary habits, physical activity (PA) and a variety of renal/urinary disorders. However, only a few studies have used Mendelian randomisation analyses to explore the causal relationship between dietary habits, physical activity and a range of renal/urinary diseases.

Methods

The exposure and outcome datasets were sourced from the BioBank, FinnGen, and the NHGRI-EBI databases. The exposure dataset comprised of 20 dietary patterns and 4 PA modalities, while the outcome dataset included 19 renal/urological disorders. The primary methods employed for MR analyses were inverse variance weighted. Heterogeneity and multiplicity analyses were conducted to ensure the validity of the results.

Results

In terms of dietary

SUBMITTER: Zhao C 

PROVIDER: S-EPMC12816814 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature