The consequences of percutaneous transhepatic biliary drainage (PTBD) in patients with tumoral obstructive jaundice: A retrospective study and review of literature.

ABSTRACT:

Background

Percutaneous transhepatic biliary drainage (PTBD) is widely used in malignant obstructive jaundice (MOJ), but most series report aggregate complication rates without stratification by tumor type. This limits individualized risk counseling and hampers benchmarking across centers.

Objective

To evaluate short-term outcomes of PTBD in a large single-center cohort, with a focus on tumor-specific complication patterns using patient-level attribution and robust statistical methods.

Methods

We retrospectively analyzed 453 patients with MOJ undergoing PTBD (2017-2022). Complications within 30 days were recorded at the patient level, with downstream sequelae attributed to the index event. Exact tests and Firth penalized logistic regression were applied to mitigate sp

SUBMITTER: Jalili J 

PROVIDER: S-EPMC12816842 | biostudies-literature | 2026 Jun

REPOSITORIES: biostudies-literature