Separating the forest from the palm trees: Individual variation in a presurgical language mapping task.

ABSTRACT:

Background

Selecting optimal tasks for language mapping in neurosurgical patients poses challenges that are exacerbated by mismatches in practice between presurgical and intraoperative evaluations. To help align practices, we evaluated a functional MRI version of a semantic association task increasingly used during intra-operative assessment of awake neurosurgery patients. Using a recently proposed consistency mapping approach, we characterise task fMRI activation reliability across individuals, visits, and scan cohorts.

Methods

FMRI data were acquired during an adapted Pyramids and Palm Trees Task (PPTT) in 15 healthy controls and 54 pre-surgical patients with a glioma. A new implementation of threshold-weighted overlap mapping (TWOM) was used to evaluate: 1. inter-individu

SUBMITTER: Voets NL 

PROVIDER: S-EPMC12816848 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature