Estimates and predictors of HIV viral non-suppression in South African adults on antiretroviral treatment.

ABSTRACT:

Introduction

Viral suppression estimates are essential for monitoring the performance of HIV programmes. South Africa introduced dolutegravir (DTG)-based antiretroviral therapy (ART) in 2019. We sought to generate updated estimates of viral suppression in South African adults on ART and investigate predictors of viral non-suppression.

Methods

This retrospective cohort study used data from seven South African cohorts participating in the International epidemiology Databases to Evaluate AIDS collaboration. Three main analyses were performed using a viral suppression threshold of 1000 HIV RNA copies/ml. In the first analysis, we fitted a logistic regression model using the full data from the study period (2005-2023). Then, in two causal analyses, we used logistic regression wit

SUBMITTER: Moolla H 

PROVIDER: S-EPMC12816880 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature