Influence of surface characteristics on the in vitro stability and cell uptake of nanoliposomes for brain delivery.

ABSTRACT: In contemporary research, there is a clear emphasis on the physicochemical characteristics and effectiveness of nanoliposomal (NLs) formulations. However, there has been minimal focus on elucidating nano-bio interactions and understanding the behavior of these formulations at organ and cellular levels. Specifically, it is widely recognized that when exposed to biological fluids, nanodelivery systems, including NLs, rapidly interact with various biomolecules which have a significant impact on the functionality and fate of the nanosystems but also influence cellular biological functions. Hence, the primary objective of this study was to elucidate the evolution of physicochemical characteristics and surface properties of NLs in biorelevant media. Additionally, in order to point out the influe

SUBMITTER: Shalabalija D 

PROVIDER: S-EPMC12816991 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature