In Vitro Evaluation and Network Pharmacology Analysis of the Antimicrobial Activity of <i>Pistacia lentiscus</i>.

ABSTRACT:

Background

Chios mastic gum, a natural resin derived from the mastic tree, has a history of traditional use for its beneficial effects on the gastrointestinal system, its anti-inflammatory properties, and its antimicrobial activity.

Objective

This study aimed to integrate network pharmacology and standardized in vitro analyses to elucidate the antimicrobial mechanisms and therapeutic potential of P. lentiscus phytochemicals.

Material and methods

This study employed a systematic methodology integrating data mining, network construction, and network analysis to explore the intricate relationships between the constituents of mastic gum and their diverse biological targets. The primary active compounds of P. lentiscus were identified through multiple

SUBMITTER: Ganeshkumar A 

PROVIDER: S-EPMC12817137 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature