Predicting Significant Blood Pressure Reduction Through Ambulatory Blood Pressure Monitoring in Patients With Obstructive Sleep Apnea Treated With Continuous Positive Airway Pressure.

ABSTRACT:

Objective

Continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea (OSA) results in a modest reduction in blood pressure. This study aimed to identify parameters from 24-h ambulatory blood pressure monitoring (ABPM) that are predictive of treatment response.

Methods

Treatment-naïve patients with OSA were prospectively recruited from the Centre for Sleep Medicine and Science at Beijing Anzhen Hospital between July 2023 and April 2025. All participants underwent 24-h ABPM assessments before and after 3-month CPAP therapy. Correlations between the baseline ABPM data and post-CPAP changes in blood pressure were analyzed. Multivariate analysis was used to determine whether specific baseline blood pressure cutoffs independently predicted a clinically signific

SUBMITTER: Jiao Y 

PROVIDER: S-EPMC12817275 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature