Behavioral Economic and Staffing Strategies To Increase Adoption of the ABCDEF Bundle in the Intensive Care Unit (BEST ICU): study protocol for a multi-site stepped-wedge cluster randomized controlled trial in the USA.

ABSTRACT:

Background

Despite its proven safety and effectiveness at liberation from mechanical ventilation, ABCDEF (Assess, prevent, and manage pain; Both spontaneous awakening and breathing trials; Choice of analgesia/sedation; Delirium: assess, prevent, and manage; Early mobility/exercise; and Family engagement/empowerment) bundle performance in everyday intensive care unit (ICU) practice remains disappointingly low. This evidence-to-practice gap significantly contributes to the excessively high morbidity, mortality, costs, and disparities associated with current critical care delivery. This study will evaluate the effects of two discrete, behavioral economic, and implementation science-based strategies on ABCDEF bundle adoption and patient-centered outcomes.

Methods

The Behavioral

SUBMITTER: Vasilevskis EE 

PROVIDER: S-EPMC12817409 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature