Characterization of urinary Escherichia coli isolates in HIV-seropositive women with asymptomatic bacteriuria in Western Ghana.

ABSTRACT:

Background

Asymptomatic bacteriuria (ASB), a precursor of urinary tract infection (UTI), is highly prevalent among people living with HIV (PLHIV). In this study, we characterized urinary Escherichia coli isolated from PLHIV with asymptomatic bacteriuria.

Methods

Urine samples from women living with HIV (WLHIV) were cultured, and bacteria isolates were identified using MALDI TOF biotyper. Antimicrobial susceptibility test was performed on isolates and genes encoding virulence factors and integrases were screened using Multiplex PCR and gel imaging. Patients' predictor variables like WHO disease staging, Highly Active Antiretroviral Therapy (HAART) duration and viral load were extracted from patient folders using a structured questionnaire.

Results

The mean age of our 4

SUBMITTER: Amegbletor HK 

PROVIDER: S-EPMC12817762 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature