One Anastomosis Gastric Bypass in Patients With a BMI ≥50 kg/m²: A Systematic Review and Single-Arm Meta-Analysis of Outcomes.

ABSTRACT:

Purpose

The prevalence of individuals with obesity classes 4 and 5 is increasing, with no optimal surgical approach identified. With the rising popularity of one anastomosis gastric bypass (OAGB), we conducted a single-arm meta-analysis to assess its outcomes in this population.

Materials and methods

A comprehensive search of PubMed, Scopus, EMBASE, and Cochrane identified studies on OAGB reporting weight loss, comorbidity remission, and complications. Statistical analysis was performed using RStudio 4.4.1. Heterogeneity was assessed using the Cochrane Q test and I² statistics.

Results

Seventeen studies including 2,274 patients (mean age, 40.44 years), were identified. The analysis revealed a rising trend up to 24 months, with a pooled excess weight loss (%

SUBMITTER: Mahran MMS 

PROVIDER: S-EPMC12817813 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature