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Risk prediction models for delirium in ICU patients: a systematic review and critical appraisal.


ABSTRACT:

Objective

This systematic review aimed to critically appraise the methodological quality, predictive performance, and clinical applicability of published risk prediction models for delirium in adult intensive care unit patients.

Methods

We searched PubMed, Embase, Web of Science, and the Cochrane Library from inception to April 8, 2025. Eligible studies were observational cohorts developing or validating multivariable prediction models for ICU delirium in adults (≥ 18 years). The review protocol was registered in PROSPERO (CRD420251028221). Study selection and data extraction followed the CHARMS checklist. Risk of bias and applicability were assessed using the Prediction Model Risk of Bias Assessment Tool (PROBAST).

Results

A total of 27 studies, encompassing 26 predi

SUBMITTER: Chen WH 

PROVIDER: S-EPMC12817868 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature