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Evaluating the short-term and long-term therapeutic effects of immunoadsorption compared with plasma exchange in chronic inflammatory demyelinating polyneuropathy: a long-term, prospective, observational study.


ABSTRACT:

SUBMITTER: Elmas Z 

PROVIDER: S-EPMC12818062 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature

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Evaluating the short-term and long-term therapeutic effects of immunoadsorption compared with plasma exchange in chronic inflammatory demyelinating polyneuropathy: a long-term, prospective, observational study.

Elmas Zeynep Z   Herrmann Christine C   Kramer Kathrin K   Soylu Oender O   Roemer Vanessa V   Jagodzinski Luisa L   Richter Lars L   Wiesenfarth Maximilian M   Fangerau Tanja T   Jung Stefanie S   Gastl Regina R   Rosenbohm Angela A   Weishaupt Jochen H JH   Senel Makbule M   Mayer Benjamin B   Tumani Hayrettin H   Dorst Johannes J  

EClinicalMedicine 20260108


<h4>Background</h4>Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune-inflammatory disease of the peripheral nervous system. Corticosteroids, intravenous immunoglobulins (IVIGs), and plasma exchange (PLEX) constitute the main therapeutic options, but immunoadsorption (IA) represents a noteworthy alternative to PLEX due to its excellent tolerability and its capability to remove higher rates of autoimmune antibodies. However, evidence of its therapeutic value in CIDP is low,  ...[more]

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