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The development of aperiodic neural activity in the human brain.


ABSTRACT: The neurophysiological mechanisms supporting brain maturation are fundamental to attention and memory capacity across the lifespan. Human brain regions develop at different rates, with many regions developing into the third and fourth decades of life. Here, in this preregistered study ( https://osf.io/gsru7 ), we analysed intracranial electroencephalography recordings from widespread brain regions in a large developmental cohort. Using task-based (that is, attention to to-be-remembered visual stimuli) and task-free (resting-state) data from 101 children and adults (5.93-54.00 years, 63 males; n electrodes = 5,691), we mapped aperiodic (1/ƒ-like) activity, a proxy of neural noise, where steeper slopes indicate less noise and flatter slopes indicate more noise. We reveal that aperiodic slope

SUBMITTER: Cross ZR 

PROVIDER: S-EPMC12818177 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature