Antimicrobial susceptibility testing of <i>Aggregatibacter Actinomycetemcomitans</i> can be performed using the EUCAST medium for anaerobic bacteria.

ABSTRACT:

Background

The oral bacterium Aggregatibacter actinomycetemcomitans (Aa) is associated with infectious diseases treated with antibiotics, but specific recommendations for antimicrobial susceptibility testing (AST) of the species do not yet exist. Objective To evaluate the possibility to perform AST of Aa following EUCAST guidelines using FAA-HB and 20 h incubation.

Method

Twenty-nine Aa strains were analysed using disk diffusion on FAA-HB media from three manufacturers. Plates with with ampicillin and azithromycin disks were incubated in 5% CO₂ and anaerobic conditions and examined after 20 and 44 h. Strains were additionally tested with the agar dilution method, and inhibition zone diameters (IZD) were correlated to the minimal inhibit

SUBMITTER: Jensen AB 

PROVIDER: S-EPMC12818291 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature