Development of a Tunable Dextran-PCL Biomaterial Photoink for High-Resolution DLP 3D Printing in Biomedical Applications.

ABSTRACT: Digital light processing (DLP) is a technique that offers higher printing speeds and high spatial resolution compared to other additive manufacturing techniques. However, in biomedical applications, the biomaterials used do not provide a good balance between biocompatibility, mechanical performance, and controlled degradation. To overcome these limitations, this study aims to develop a biomaterial photoink formulation using two FDA-approved polymers. Dextran, which has high biocompatibility, was modified with glycidyl methacrylate to introduce photoreactive groups, and poly(ε-caprolactone) (PCL), a biodegradable synthetic polymer known for its mechanical reinforcement properties and slower degradation rate, was functionalized with 2-isocyanatoethyl methacrylate. To optimize the formulation

SUBMITTER: Escobar ICP 

PROVIDER: S-EPMC12818721 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature