Synchronous Rectal Adenocarcinoma and Sigmoid Gastrointestinal Stromal Tumor: A Case Report.

ABSTRACT:

Introduction

The synchronous presentation of a colorectal adenocarcinoma and a gastrointestinal stromal tumor (GIST) is a rare clinical event that poses significant diagnostic and therapeutic challenges. These two malignancies arise from distinct histogenetic origins and are typically managed with different treatment paradigms. The incidental discovery of a GIST during the workup for a more symptomatic adenocarcinoma complicates surgical planning and requires a comprehensive, multidisciplinary approach to ensure optimal oncologic outcomes.

Case presentation

An 85-year-old female presented with a 6-month history of debilitating fecal incontinence, tenesmus, rectal bleeding, and a 13 kg weight loss. Diagnostic evaluation, including imaging and endoscopy, identified two separat

SUBMITTER: Al-Bitar A 

PROVIDER: S-EPMC12818895 | biostudies-literature | 2026 Jan-Dec

REPOSITORIES: biostudies-literature