Alterations in intramuscular connective tissue in hypertonic muscle: a scoping review.

ABSTRACT:

Introduction

Muscle hypertonia is a common symptom in patients with upper motor neuron disorders. To date, the role of intramuscular connective tissue (IMCT) alterations in hypertonic muscle has not been fully explored. This review aimed to identify and characterize alterations in IMCT components in hypertonic muscle in central neurological disorders.

Methods

This scoping review included studies investigating IMCT alterations in hypertonic muscles resulting from central neurological disorders. Four electronic databases, including PubMed/Medline, CINAHL, Web of Science, and Scopus, were searched to identify relevant studies published prior to 20 July 2025. The review followed the Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) checklist. The ri

SUBMITTER: Zhao X 

PROVIDER: S-EPMC12819202 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature