Development and validation of a prognostic nomogram for predicting hypostatic pneumonia risk in large vessel occlusion stroke after endovascular therapy patients.

ABSTRACT:

Background

Post-stroke hypostatic pneumonia (HP) significantly impairs neurological recovery and worsens prognosis in patients with acute ischemic stroke with large vessel occlusion (AIS-LVO). This study aimed to develop and validate a prognostic nomogram for predicting hypostatic pneumonia risk following endovascular therapy (EVT) in AIS-LVO patients.

Methods

We retrospectively analyzed 650 consecutive AIS-LVO patients who underwent endovascular therapy with mechanical ventilation at Dongguan Hospital of Guangzhou University of Chinese Medicine from September 2018 to March 2025. After applying inclusion/exclusion criteria, 412 patients were randomly split into two groups: training (n = 288) and validation (n = 124), maintaining a 7:3 ratio. Using least absolut

SUBMITTER: Zhu J 

PROVIDER: S-EPMC12819305 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature