Sensor-based quantification of items used in the MDS-UPDRS-III scale: repetitive lower-limb movements in healthy human participants.

ABSTRACT:

Background

The Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) is used as a standardized approach to assess motor function in Parkinson's disease (PD). This assessment is based on the examiner's subjective judgement and is therefore variable. While quantitative approaches have been evaluated for upper-limb movements, data is scarce on lower-limb movements. Thus, our aim was to implement and assess a setup to quantify lower-limb movements as defined in the MDS-UPDRS in healthy participants introducing new parameters for smoothness and acceleration patterns.

Methods

Twenty-three participants (age-range = 21-31 years) performed five 20-s trials for both lower-limb movement tasks from the MDS-UPDRS-III, i.e., toe tapping (item 3.7) and leg agility

SUBMITTER: Hunziker S 

PROVIDER: S-EPMC12819309 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature