Characteristics of dysarthria in patients with spinocerebellar degeneration and multiple system atrophy: a cross-sectional and longitudinal study using the Frenchay Dysarthria Assessment Second Edition (FDA-2).

ABSTRACT:

Purpose

The purpose of this study was to evaluate the dysarthria of patients with spinocerebellar degeneration and multiple system atrophy (SCD/MSA) cross-sectionally and longitudinally using the Frenchay Dysarthria Assessment Second Edition (FDA-2), which provides a comprehensive assessment of dysarthria, and to clarify characteristic patterns and longitudinal changes.

Materials and methods

A total of 21 patients with SCD and MSA were included. Patients' dysarthria was assessed using the FDA-2 and the Scale for the Assessment and Rating of Ataxia (SARA) item 4(SARA speech) at intervals of ≥ 12 months. Changes over time were examined with a paired t-test and Wilcoxon's signed-rank test. Multiple regression analysis explored determinants of speech intelligibility, with FDA-2

SUBMITTER: Kawabata A 

PROVIDER: S-EPMC12819311 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature