Association between advanced lung cancer inflammation index levels and ischemic stroke in patients with atrial fibrillation: a propensity score-matching analysis.

ABSTRACT:

Introduction

Inflammation is closely associated with atrial fibrillation (AF) complicated by stroke. The Advanced Lung Cancer Index (ALI) is a comprehensive indicator of inflammation; however, its relationship with AF-related stroke is unclear. Therefore, this retrospective study was conducted to explore the correlation between ALI and ischemic stroke in patients with AF.

Methods

Patients were divided into two groups according to the optimal cutoff value of ALI: low ALI and high ALI groups. The primary outcome was ischemic stroke in patients with AF. To ensure robustness of the findings, propensity score matching, multivariate logistic regression, inverse probability weighting models, and doubly robust analysis were performed.

Results

Of 2,630 eligible patients (scree

SUBMITTER: Li Y 

PROVIDER: S-EPMC12819322 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature