Preoperative Botulinum Toxin for Complex Diaphragmatic Paralysis: A Case Series.

ABSTRACT:

Introduction

The management of giant diaphragmatic paralysis remains a significant surgical challenge, frequently associated with high rates of recurrence and the risk of developing abdominal compartment syndrome. While the use of Botulinum Toxin Type A (BTX- A) as an adjuvant therapy has been established in complex ventral hernia repair, its application in diaphragmatic paralysis is novel and sparsely documented. This study aims to present our institutional experience with BTX-A as a prehabilitation strategy in patients with complex diaphragmatic paralysis and to evaluate short- and long-term outcomes.

Materials and methods

Three patients with complex diaphragmatic paralysis underwent preoperative administration as part of a prehabilitation protocol prior to surgical repair

SUBMITTER: Sanchez Moreno L 

PROVIDER: S-EPMC12819334 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature