Prenatal exposure to acrylamide and metabolic health at 20 years of age A biomarker-based Danish cohort study.

ABSTRACT: Adult obesity and metabolic health may be influenced by prenatal exposure to acrylamide (AA). AA forms in carbohydrate-containing foods and beverages during high-temperature processing. AA disrupts metabolic homeostasis and induces adiposity in mice offspring following gestational exposure. In humans, AA has been associated with intrauterine growth restriction and childhood overweight. It is unknown if prenatal exposure to AA influences metabolic health in young adults. We examined the associations between prenatal exposure to AA and metabolic health in singletons born in 1988-1989, Denmark. Hemoglobin adducts from AA (HbAA) and glycidamide were measured in maternal blood collected at 30 weeks' gestation together with information on maternal dietary and smoking habits (n = 638). At 20 year

SUBMITTER: Tuffier S 

PROVIDER: S-EPMC12819368 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature