Safety outcomes of mucomuscular closure versus conventional clip closure in ESD of large (> 15 mm) nonpedunculated colorectal polyps (LNPCPs).

ABSTRACT:

Background and aims

Post-endoscopic submucosal dissection (ESD) electrocoagulation syndrome (PEECS) is a recognized limitation of colorectal ESD (C-ESD) associated with morbidity, additional costs, and prolonged admission. Reliable closure of C-ESD defects can decrease the incidence of PEECS. We introduce a novel mucomuscular closure technique that involves direct closure of the muscularis propria using through-the-scope clips (TTSC). We evaluate the feasibility and efficacy of the modified closure technique in prevention of post-C-ESD PEECS.

Methods

We conducted a prospective cohort study of consecutive C-ESDs at a single tertiary center between January 2017 and October 2023. Patients who underwent C-ESD with mucomuscular closure or conventional closure with TTSC were enrol

SUBMITTER: Chen TY 

PROVIDER: S-EPMC12819494 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature