Mechano-electrical-fluid interaction left-ventricle model for numerical evaluation of aortic valve hemodynamics.

ABSTRACT:

Background and objective

Aortic valve simulation has a crucial meaning for clinical applications like the prediction of transcatheter aortic valve implantation or the Ozaki procedure. One of the main aspects is the inflow boundary condition because it has a strong effect on hemodynamic flow simulation results. Most researchers adopt a 2-D profile derived from ultrasound measurements for 3-D fluid-structure interaction simulations that do not take into account several physiological effects.

Methods

A model including left ventricle contraction and blood flow in the aorta segment with aortic valve leaflets was developed. A mechano-electrical-fluidic interaction model of the left ventricle was developed to assess a 3-D profile of blood passing to the aortic valve. The effect of

SUBMITTER: Pil N 

PROVIDER: S-EPMC12819714 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature