Determinants of abnormal liver-related biomarkers in adult COVID-19 patients.

ABSTRACT:

Background

Serum hepatic injury markers indexes are altered in COVID-19 patients. We aimed to explore the factors that could be associated with abnormal serum hepatic injury markers in adult COVID-19 patients.

Methods

Eight main hepatic injury markers were examined. Demographic and hematological information, mean CT values (MCTVs) of liver and pancreas, and abdominal subcutaneous fat thickness were recorded. Regression analysis was conducted to identify factors related to abnormal hepatic injury markers.

Results

1,007 adult COVID-19 patients (444 males and 563 females) were included, among whom 697 patients (69.2%) had at least one abnormal hepatic injury markers marker. Females had lower risks of elevated Total Bilirubin (TBil), Direct Bilirubin (Dbil), ALT, AST, GGT

SUBMITTER: Zhang S 

PROVIDER: S-EPMC12819734 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature