Dietary and Urinary Iodine in Relation to Thyroid Cancer Risk: A Meta-Analysis.

ABSTRACT: IntroductionThe influence of iodine on papillary thyroid carcinoma (PTC) remains a subject of debate. This meta-analysis was conducted to evaluate the risk association between varying levels of iodine intake and the occurrence of PTC and different subtypes of thyroid carcinoma (TC), particularly papillary thyroid microcarcinoma (PTMC).MethodsFour databases-the Cochrane Library, Embase, PubMed, and Web of Science-were systematically searched for relevant studies published up until May 30, 2024. An updated search was conducted on November 20, 2025. Literature screening and information collection were performed according to predefined eligibility criteria. The Newcastle-Ottawa Scale (NOS) was used to appraise the quality of the eligible literature. Statistical analysis was performed using Sta

SUBMITTER: Li S 

PROVIDER: S-EPMC12819980 | biostudies-literature | 2026 Jan-Dec

REPOSITORIES: biostudies-literature