Dataset Information
Novel plasmid curing mediated restoration of antimicrobial sensitivity by Nigella sativa extract against multidrug resistant Staphylococcus aureus.
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ABSTRACT:
SUBMITTER: Ahmad AAM
PROVIDER: S-EPMC12820097 | biostudies-literature | 2026 Jan
REPOSITORIES: biostudies-literature
Publications
Novel plasmid curing mediated restoration of antimicrobial sensitivity by Nigella sativa extract against multidrug resistant Staphylococcus aureus.
Scientific reports 20260118 1
Plasmid-mediated antimicrobial resistance is a major contributor to infections associated with high morbidity and mortality. Given the urgent demand for effective and safe elimination of plasmids from multidrug-resistant (MDR), this study is the first to examine the potential of Nigella sativa essential oil (NSO) and thymoquinone (TQ) in eliminating antimicrobial resistance plasmid from Staphylococcus aureus. Plasmid profiles of resistant variants derived from the original MDR strains following ...[more]