The Knowledge Connector decision support system for multiomics-based precision oncology.

ABSTRACT: Precision cancer medicine aims to improve patient outcomes by providing individually tailored recommendations for clinical management based on the evaluation of biological disease profiles in multidisciplinary molecular tumor boards (MTBs). The quality of MTB decisions depends on the comprehensive, reliable, and reproducible interpretation of increasingly complex molecular data. We developed and implemented, as part of a multicenter precision oncology program, the Knowledge Connector (KC), a decision support system that integrates individual patients' molecular and clinical data with world knowledge to generate and document MTB recommendations. The KC supports data curation, database integration, and discussion based on multiomics data and provides an interface for creating a cross-institu

SUBMITTER: Hubschmann D 

PROVIDER: S-EPMC12820158 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature