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Integrated in vivo and in silico analysis of immune gene expression in cattle infected with Brucella abortus.


ABSTRACT:

SUBMITTER: Mabrouk DM 

PROVIDER: S-EPMC12820187 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature

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Integrated in vivo and in silico analysis of immune gene expression in cattle infected with Brucella abortus.

Mabrouk Dalia M DM   El-Diasty Mohamed M   Abdel-Aziem Sekena H SH  

Scientific reports 20260117 1


Brucella abortus is an intracellular pathogen that causes infection in cattle, leading to reproductive losses and posing a zoonotic risk to humans. Understanding host immune responses at the molecular level is essential for developing targeted diagnostics and control strategies. This study aimed to investigate the expression of immune-related genes in Bos taurus naturally infected with Brucella abortus using integrated in vivo and in silico approaches. The infection was characterized as chronic  ...[more]

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