Reemergence of yellow fever virus in forest and periurban settings in Brazil.

ABSTRACT:

Background

Yellow fever virus remains a major public health threat in Brazil, where recent resurgence risks affecting both forest and periurban populations. Understanding viral movement across ecological settings is critical to support early detection and prevent outbreaks.

Methods

We performed genomic surveillance in two Brazilian states, a northern Amazon region and a southeastern region, between 2023 and 2025. Human and non-human primate samples were collected across forest, rural, and urban environments. Viral genomes were generated and analyzed using phylogenetic, phylogeographic, and temporal approaches to reconstruct viral transmission patterns.

Results

Here, we show evidence of continued yellow fever virus circulation and diversification in distinct ecological

SUBMITTER: das Gracas Dantas Andrade V 

PROVIDER: S-EPMC12820255 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature