Use of non-prescription analgesic medications and survival among Black women with ovarian cancer.

ABSTRACT:

Background

Chronic inflammation and inflammatory-related exposures have been implicated in epithelial ovarian cancer (EOC) prognosis. However, no studies have evaluated whether analgesic medication use impacts survival in Black women with EOC, an understudied population with poor survival.

Methods

Leveraging data from the African American Cancer Epidemiology Study, we examined the association of pre-diagnostic analgesic medication use (aspirin, non-aspirin non-steroidal anti-inflammatory drugs [naNSAIDs], and acetaminophen) with survival among self-identified Black women diagnosed with EOC (N = 541) using multivariable Cox proportional hazards regression. Stratified analyses were conducted by comorbidities and histotype.

Results

Acetaminophen use was associated with a

SUBMITTER: Colin-Leitzinger C 

PROVIDER: S-EPMC12820352 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature