Global, regional and national burden of epilepsy in children and adolescents, 1990-2021: A systematic analysis for the Global Burden of Disease Study 2021.

ABSTRACT:

Background

Epilepsy is a common neurological disease that heavily impacts children and adolescents and carries serious physical, cognitive, psychological, social and economic consequences for patients and their caregivers.

Methods

Data was obtained via the Global Burden of Disease Study 2021. We reported numbers, rates and percentage changes of prevalence, mortality and disability-adjusted life years (DALYs).

Results

In 2021, there were 18.15 million [95% UI: 14.61-21.85] prevalent cases of epilepsy in children and adolescents worldwide, 8.24 million [5.77-11.13] of which were idiopathic epilepsy and 9.91 million [8.72-11.06] of which were secondary epilepsy. While mortality and DALY rates of idiopathic epilepsy declined between 1990 and 2021, the burden of secondary

SUBMITTER: Kim YS 

PROVIDER: S-EPMC12820917 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature