Genomic Architecture of Inbreeding Depression Associated With Hatching Failure in an Endangered Parrot.

ABSTRACT: Conservation management of endangered species increasingly relies on genomic approaches to understand how long-term small population sizes affect the fitness of extant individuals. However, despite the growing investment in genomic resources by conservation programmes, the impact that sequencing methods have on the ability to detect inbreeding-related phenomena has been largely overlooked. Here, we compare the use of whole-genome and reduced-representation sequencing approaches in 148 individuals of the critically endangered parrot, the kākāpō (Strigops habroptilus), to assess inbreeding and its effects on female reproductive success. We explore how sequencing choice influences the identification of long stretches of homozygosity across the genome (runs of homozygosity, ROH), and compare t

SUBMITTER: Foster Y 

PROVIDER: S-EPMC12820920 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature