Effect of a 24-week resistance exercise intervention on cognitive function in cognitively normal older adults: The AGUEDA randomized controlled trial.

ABSTRACT:

Introduction

The Active Gains in Brain Using Exercise During Aging (AGUEDA) trial examined the effects of a 24 week resistance exercise (RE) intervention on executive function (EF) and other cognitive domains in cognitively normal older adults.

Methods

Ninety participants (mean age, 71.8 years; 57.8% female) were randomized to an RE or control group. At baseline and 24 weeks, EF and other cognitive domains were assessed.

Results

The RE group showed significant improvements in overall EF (standardized mean difference [SMD] = 0.39, 95% confidence interval = 0.14, 0.65), with no significant between-group difference (SMD = 0.13, p = 0.37). The RE group showed a significant improvement in attentional/inhibitory control (SMD = 0.43, p < 0.001) compared to the control group,

SUBMITTER: Fernandez-Gamez B 

PROVIDER: S-EPMC12820987 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature