Non-invasive analysis of pump parameter responses to orthostatic transitions in patients with fully magnetically levitated left ventricular assist devices.

ABSTRACT:

Aims

Despite the excellent clinical outcomes of the HeartMate 3 (HM3) left ventricular assist device, the current pump monitoring limits in-depth pump data analysis. This study investigated HM3 pump parameters collected non-invasively with HM3 Snoopy during orthostatic transitions (OTs).

Methods and results

In this single-centre cohort study, a standardized OT protocol was developed, involving postural changes between supine, seated, and standing. Data were recorded using the HM3 Snoopy and a Holter electrocardiogram. Pump flows (Q_MIN, Q_MEAN, Q_MAX), pulsatility index (PI), pump speed, MagLev parameters, and heart rate were synchronized per second. The primary outcome was the identification of distinct orthostatic pump flow response phenotypes

SUBMITTER: Ruoff L 

PROVIDER: S-EPMC12821056 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature