Antiphospholipid syndrome presents with aortic thrombosis and central venous catheter-related thrombosis: a case report.

ABSTRACT:

Background

Antiphospholipid syndrome (APS) is a prothrombotic autoimmune disorder in which perioperative factors-particularly cardiopulmonary bypass-may amplify hypercoagulability. Evidence and consensus guidance for APS management around cardiovascular surgery remain limited. A 37-year-old man with a large, highly mobile thrombus in the ascending aorta underwent surgical thrombectomy under cardiopulmonary bypass. Preoperative testing showed only leukocytosis, slightly shortened activated partial thromboplastin time (APTT) and mild D-dimer elevation; all other findings were unremarkable. Ten days postoperatively, removal of a nontunneled right internal jugular central venous catheter (CVC) was unexpectedly impeded by catheter-related thrombosis (CRT) despite prophylactic anticoagul

SUBMITTER: Chen Y 

PROVIDER: S-EPMC12821187 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature