Improved detection of Listeria monocytogenes outbreaks using whole genome sequencing, Gipuzkoa, Northern Spain, 2010 to 2022.

ABSTRACT:

Background

Listeria monocytogenes is a major foodborne pathogen responsible for severe infections, mainly affecting pregnant women, the elderly, and immunocompromised individuals. In Spain, listeriosis has been insufficiently studied using modern molecular techniques, and genomic data from clinical isolates remain scarce. Long‑term genomic surveillance based on whole genome sequencing (WGS) has not yet been systematically applied. WGS has proven to be a powerful method for outbreak detection and for revealing transmission dynamics that remain hidden to conventional epidemiology. This study aimed to characterise clinical L. monocytogenes isolates from Gipuzkoa, a region in northern Spain, collected over more than a decade, and to investigate their genetic diversity, phylogenetic rel

SUBMITTER: Vallejo P 

PROVIDER: S-EPMC12821238 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature