Optimal resistance training strategies for knee osteoarthritis symptom relief: a systematic review and network meta-analysis.

ABSTRACT:

Aims

To determine the most effective resistance training (RT) type and the optimal intensity, duration, and number of repetitions for patients with knee osteoarthritis (KOA).

Methods

PubMed, MEDLINE, Embase, CENTRAL, and Web of Science were searched from inception to April 2025 for randomized controlled trials (RCTs) of exercise for KOA. Bayesian network meta-analyses were conducted. The outcomes of pain, stiffness, and function were expressed as standardized mean differences (SMDs) with 95% credible intervals (CrI).

Results

The analysis included 46 RCTs with 3463 participants. High-speed RT was identified as the most effective type, significantly improving pain (SMD: -1.35, 95% CrI: -1.89 to -0.81), stiffness (SMD: -1.26, 95% CrI: -1.81 to -0.70), and function (SMD:

SUBMITTER: Yang Y 

PROVIDER: S-EPMC12821314 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature