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Long-term mortality in pediatric sepsis: a systematic review and meta-analysis.


ABSTRACT:

Background

Pediatric sepsis represents a significant factor in the mortality rates among children, with survivors remaining highly fragile during the period following discharge. While in-hospital and short-term mortality have been widely studied, the long-term mortality of pediatric sepsis is not adequately synthesized or appreciated. This study aims to estimate the long-term mortality associated with pediatric sepsis, providing a basis for optimizing post-discharge surveillance and care protocols.

Methods

This systematic review and meta-analysis followed PRISMA guidelines and was registered in PROSPERO (CRD420251137504). Exhaustive searches were conducted in PubMed, Embase, the Cochrane Library, and Web of Science for studies published from the inception of each database to

SUBMITTER: Lv Y 

PROVIDER: S-EPMC12821344 | biostudies-literature | 2026 Dec

REPOSITORIES: biostudies-literature