Associations of Muscle Strength and Functional Power with Longitudinal Change in HR-pQCT Bone Parameters: The Osteoporotic Fractures in Men (MrOS) Study.

ABSTRACT: Both bone and muscle function decline with age and are anatomically and functionally related. However, whether and to what extent muscle function (ie, strength and power) may predict longitudinal changes in bone microarchitecture and strength is unclear. The Osteoporotic Fractures in Men (MrOS) Study included assessments of peak jump power (W) from a force plate and maximum grip strength (kg) from a dynamometer, both normalized to body weight at Visit 4 (2014-2016). We investigated associations of jump power and grip strength with annual % change in volumetric bone mineral density (BMD), microarchitecture, and strength at the distal tibia (DT) and radius (DR) from high-resolution peripheral quantitative computed tomography (HR-pQCT) between Visit 4 and Visit 5 (2020-2022; 6.2 ± 0.6 yr foll

SUBMITTER: Heilmann NZ 

PROVIDER: S-EPMC12821768 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature