Factors related to cervicogenital high-risk human papillomavirus persistence among Chinese women: a nationwide multi-center cohort study.

ABSTRACT:

Background

Persistent infection with high-risk human papillomavirus (HR-HPV) is a necessary cause of cervical cancer and its precancerous lesions. This study aimed to identify factors associated with HR-HPV persistence in Chinese women.

Methods

This study is a population-based, nationwide, multi-center prospective cohort study initiated in 2017, and a total of 10,481 women undergoing cervical cancer screening were enrolled. A subset of 1,684 women who tested HR-HPV positive at baseline were included in the analysis. The results of their HPV testing at baseline and during three follow-up visits (2018-2020) were used to assess 1-, 2-, and 3-year HR-HPV persistence. Variables with statistically significant associations in univariate analyses, expressed as odds ratios (ORs) with

SUBMITTER: Li J 

PROVIDER: S-EPMC12821850 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature