Ultrasound-enhanced and cell-traction-induced piezoelectric scaffolds for repairing bone defects.

ABSTRACT: The global increase in traumatic accidents and aging population has brought bone tissue injury and disease to the forefront of global health concerns. Traditional treatment methods face significant challenges, emphasizing the urgent need for advanced bone tissue repair techniques. The bioelectric phenomenon in natural bones is essential for bone development and fracture healing. Therefore, developing innovative repair strategies that replicate or enhance this electric field is expected to promote bone tissue repair and integration. Developing new electroactive tissue engineering scaffolds based on electromechanical interactions between cells and the extracellular matrix is essential. This article introduces a piezoelectric scaffold, initially fabricated using melt electro-writing, and then

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12821937 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature