Association between De Ritis ratio and mortality in individuals with diabetes or prediabetes: evidence from NHANES (1999-2018).

ABSTRACT:

Background

The De Ritis ratio (AST/ALT) has emerged as a potential biomarker for metabolic dysfunction, but its association with mortality in individuals with diabetes or prediabetes remains inadequately explored. This study investigated the relationship between the De Ritis ratio and mortality in this population.

Methods

We analyzed data from 23,873 participants with diabetes or prediabetes from the National Health and Nutrition Examination Survey (NHANES) 1999-2018. Participants were stratified into quartiles based on De Ritis ratio values. Cox proportional hazards regression models were employed to assess mortality risk, adjusting for demographic, lifestyle, and clinical factors. Restricted cubic spline (RCS) analysis examined potential non-linear relationships.

Result

SUBMITTER: Long HD 

PROVIDER: S-EPMC12822107 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature