Soaring hospitalization burden and a paradigm shift to non-aids-defining events among people living with HIV in Western China: a decade-long retrospective cohort study (2013-2022).

ABSTRACT:

Objectives

Despite the success of antiretroviral therapy (ART), people living with HIV (PLWH) face an evolving burden of hospitalizations, increasingly driven by non-AIDS-defining events (nADEs). Comprehensive longitudinal data on these trends, particularly from resource-limited settings in Western China, remain scarce. This study aimed to characterize decade-long hospitalization patterns, distinguish between ADEs and nADEs admissions, and identify key risk factors among PLWH in Luzhou, China.

Methods

A retrospective cohort study was conducted using data from Luzhou's HIV/AIDS Comprehensive Response Information Management System (CRIMS) for 12,937 PLWH diagnosed between 2013 and 2022. The primary outcome was hospitalization, categorized as ADEs or nADEs. Annual hospitalizati

SUBMITTER: Chen J 

PROVIDER: S-EPMC12822277 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature