Association of metabolic score for visceral fat and risk of arterial stiffness and long-term all-cause mortality: a 10-year prospective study.

ABSTRACT:

Background

This study aimed to investigate the relationship between the Metabolic Score for Visceral Fat (METS-VF) and all-cause mortality among community-dwelling older adults, and to evaluate the potential mediating effect of brachial-ankle pulse wave velocity (baPWV) in this relationship.

Methods

A prospective cohort of 1,794 community-dwelling elderly Chinese (mean age 71.2) was followed for a median of 9.9 years. METS-VF and baPWV were measured at baseline. We performed Cox regression to determine hazard ratios across METS-VF quartiles, restricted cubic splines (RCS) to examine potential nonlinearity, and mediation analysis to assess the effect mediated through baPWVA.

Results

The mean age of the 1,794 participants was 71.2 years. Over a median follow-up of 9.9 y

SUBMITTER: Chen Y 

PROVIDER: S-EPMC12822323 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature