Neuropathic pain in knee osteoarthritis: functional burden beyond cartilage thickness-a cross-sectional study.

ABSTRACT:

Objective

Knee osteoarthritis (OA) is a common degenerative condition leading to pain and disability. While structural changes such as cartilage loss are central to OA pathology, neuropathic pain (NP) may also contribute to symptom severity and outcomes. This study cross-sectional study aimed to evaluate the association between femoral cartilage thickness and NP in patients with knee OA, and to assess its impact on pain, function, and quality of life.

Results

Sixty patients with knee OA were evaluated and classified into NP and non-NP groups using the painDETECT questionnaire (30 per group). Compared with non-NP patients, those with NP reported significantly higher pain scores (VAS: 4.70 vs. 3.37, p < 0.001), worse functional impairment (WOMAC: 71.0 vs. 55.9, p = 0.002), and

SUBMITTER: Javad PS 

PROVIDER: S-EPMC12822334 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature