Impact of Preeclampsia Duration on Long-Term Cardiovascular Disease Risk.

ABSTRACT:

Background

Preeclampsia is associated with increased risk of subsequent maternal cardiovascular diseases (CVD) compared with normotensive pregnancies. We examined whether a longer duration between preeclampsia diagnosis and delivery is associated with a higher CVD risk before age 55.

Methods

Nationwide health registry data from 2 Finnish cohorts were used: FINNPEC (n=1139) and FinnGen (n=3603). Exposure was the duration from preeclampsia diagnosis to delivery in days. Outcome was a composite CVD, including new-onset hypertensive diseases, ischemic heart diseases, cerebral/precerebral arterial diseases, and peripheral artery diseases diagnosed before age 55. Cox proportional hazards models were used to estimate the risk of composite CVD for each day between preeclampsia diagn

SUBMITTER: Keitaanpaa N 

PROVIDER: S-EPMC12822770 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature